In some cultures, skulls are associated with death and the afterlife, and can be a symbol of mortality and the impermanence of life. They can also represent the transience of material possessions and the need to focus on spiritual values. In other cultures, skulls are seen as a symbol of rebirth and transformation. This is because a skull is a container that held the brain, which is associated with the mind and consciousness. Some spiritual traditions see the skull as a symbol of the death of the ego and the rebirth of the true self.

Orange calcite is thought to have a positive impact on emotional, physical, and spiritual well-being.